Hope for haemophilic patients with hepatitis.
نویسنده
چکیده
منابع مشابه
The natural history of HCV in a cohort of haemophilic
Aim—This study describes the long term follow up of haemophilic patients infected with hepatitis C virus (HCV) between 1961
متن کاملLong-term evolution of the 5'UTR and a region of NS4 containing a CTL epitope of hepatitis C virus in two haemophilic patients.
Haemophilic patients exposed to unsterilized clotting factor concentrates prior to 1985 have become infected with hepatitis C virus (HCV). We have studied the sequence evolution of the 5'UTR and a region of NS4 over 12 years in one human immunodeficiency virus (HIV) positive haemophilic patient and 14 years for one HIV negative haemophilic patient. One sample each year from the date of HCV infe...
متن کاملNon-invasive investigation of liver disease in haemophilic patients.
Liver biopsy specimens previously taken from 16 haemophilic patients with chronic non-A, non-B hepatitis were reviewed. The degree of fibrosis correlated with serum procollagen III peptide (sPIIIP) concentrations, measured both at the time of biopsy and 4.25 years later. Two patients with extremely high sPIIIP concentrations had collateral veins on computed tomography, suggesting portal hyperte...
متن کاملOutcome of orthotopic liver transplantation in patients with haemophilia.
BACKGROUND Many patients with haemophilia have developed cirrhosis or hepatocellular carcinoma due to transfusion acquired chronic viral hepatitis. AIMS To assess the long term outcome of all haemophilic patients reported to have undergone orthotopic liver transplantation. METHODS Transplant centres of patients identified by medical database search were contacted and survival data assessed ...
متن کاملTreatment of chronic hepatitis C in haemophilic patients with interferon and ribavirin: a meta-analysis.
BACKGROUND Hepatitis C virus (HCV) infection is a major cause of morbidity and mortality among haemophilic patients who were treated with clotting factor concentrates before the availability of virus-inactivated factors in the mid 1980s. In order to analyse the effect of the current combination anti-HCV treatment [i.e. ribavirin plus interferon (IFN)] in this subset of HCV-infected patients, we...
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ورودعنوان ژورنال:
- Gut
دوره 39 6 شماره
صفحات -
تاریخ انتشار 1996